In 1918, Shandong Province Industriy Department allocated funds of 40810.00 prepared to build Qingzhou silkworm and silk farm on the base of Qingzhou state office.
In 1920, Qingzhou silkworm and silk farm introduced 69 silkworm from domestic and Japan for experiment.
In 1925, Qingzhou silkworm and silk Farm was reorganised to silkworm production farm.

In 1930, Silkworm production farm was reorganized to provincial sericulture experiment farm.The maximum production capacity is 18400 box of hybrid eggs.
In 1937, Japan launched an all-out war of aggression against China, Improvement of Shandong modern Mulberry and silkworm in shandong province dies on the vine unfortunately.